Thierry Arnould Selected Research

Neoplasms (Cancer)

1/2020	MPV17 does not control cancer cell proliferation.
5/2015	Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment.
5/2015	Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis.
1/2015	Heat-modified citrus pectin induces apoptosis-like cell death and autophagy in HepG2 and A549 cancer cells.
9/2014	Unraveling biochemical pathways affected by mitochondrial dysfunctions using metabolomic approaches.
12/2013	Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types.
9/2012	TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.
1/2012	Hypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell types.
10/2010	BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway.
1/2009	Up-regulation of cathepsin B expression and enhanced secretion in mitochondrial DNA-depleted osteosarcoma cells.

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Thierry Arnould Research Topics

Disease

10	Neoplasms (Cancer) 01/2020 - 01/2009
6	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 06/2005
6	Hypoxia (Hypoxemia) 05/2015 - 10/2010
4	Obesity 02/2018 - 01/2009
2	Carcinogenesis 04/2015 - 01/2009
2	Nervous System Diseases (Neurological Disorders) 09/2014 - 06/2012
2	Atherosclerosis 01/2013 - 11/2010
2	Inflammation (Inflammations) 06/2012 - 01/2011
2	Hypersensitivity (Allergy) 01/2012 - 05/2011
2	MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers) 01/2012 - 06/2005
2	Hepatocellular Carcinoma (Hepatoma) 10/2010 - 02/2004
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2018
1	Hypertrophy 02/2018
1	Weight Loss (Weight Reduction) 01/2018
1	Body Weight (Weight, Body) 01/2018
1	Breast Neoplasms (Breast Cancer) 05/2015
1	Infections 04/2015
1	Bacterial Infections (Bacterial Infection) 04/2015
1	Dyslipidemias (Dyslipidemia) 01/2013
1	Insulin Resistance 01/2013
1	Atherosclerotic Plaque (Atheroma) 01/2013
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2012
1	Tauopathies 06/2012
1	Alzheimer Disease (Alzheimer's Disease) 06/2012
1	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2012
1	Starvation 01/2012
1	MELAS Syndrome (Syndrome, MELAS) 01/2012
1	B-Cell Lymphoma (Lymphoma, B Cell) 05/2011
1	Lymphoma (Lymphomas) 05/2011
1	Asthma (Bronchial Asthma) 01/2011
1	Osteosarcoma (Osteogenic Sarcoma) 01/2009
1	Multiple Symmetrical Lipomatosis (Lipomatosis, Familial Benign Cervical) 06/2005
1	Mitochondrial cytopathy 06/2005
1	Fibrosarcoma 04/2004
1	Cholestasis 10/2003
1	Necrosis 10/2003

Drug/Important Bio-Agent (IBA)

6	Etoposide (VP 16)FDA LinkGeneric 04/2015 - 10/2010
5	Proteins (Proteins, Gene)FDA Link 12/2013 - 01/2009
4	Mitochondrial DNA (mtDNA)IBA 01/2020 - 01/2009
4	LipidsIBA 01/2013 - 01/2009
3	Triglycerides (Triacylglycerol)IBA 02/2018 - 06/2005
3	MicroRNAs (MicroRNA)IBA 04/2015 - 01/2011
2	Small Interfering RNA (siRNA)IBA 01/2020 - 10/2010
2	Biomarkers (Surrogate Marker)IBA 05/2015 - 09/2012
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2015 - 09/2012
2	CalciumIBA 04/2015 - 01/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2014 - 01/2009
2	DNA (Deoxyribonucleic Acid)IBA 09/2014 - 04/2006
2	StaurosporineIBA 01/2012 - 05/2011
2	Caspase 3 (Caspase-3)IBA 01/2012 - 05/2011
2	Cathepsin BIBA 05/2011 - 01/2009
1	Mitochondrial Uncoupling ProteinsIBA 01/2019
1	Hormones (Hormone)IBA 11/2018
1	ApelinIBA 01/2018
1	alpha-MSHIBA 01/2018
1	CarboxypeptidasesIBA 01/2018
1	Propranolol (Inderal)FDA LinkGeneric 05/2015
1	Sirolimus (Rapamycin)FDA Link 05/2015
1	Pattern Recognition ReceptorsIBA 04/2015
1	Pathogen-Associated Molecular Pattern MoleculesIBA 04/2015
1	citrus pectinIBA 01/2015
1	PectinsIBA 01/2015
1	Protein AggregatesIBA 09/2014
1	Adenosine Triphosphate (ATP)IBA 09/2014
1	Insulin (Novolin)FDA Link 01/2013
1	Fenofibrate (CiL)FDA LinkGeneric 01/2013
1	LDL Receptors (LDL Receptor)IBA 01/2013
1	Rosiglitazone (Avandia)FDA Link 01/2013
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2013
1	AdiponectinIBA 01/2013
1	tau Proteins (tau Protein)IBA 06/2012
1	quinone (benzoquinone)IBA 01/2012
1	Cytochromes c (Cytochrome c)IBA 01/2012
1	Heme Oxygenase-1IBA 01/2012
1	Oxidoreductases (Dehydrogenase)IBA 01/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	CaspasesIBA 01/2012
1	NAD (NADH)IBA 01/2012
1	Messenger RNA (mRNA)IBA 01/2011
1	Matrix Metalloproteinases (MMPs)IBA 01/2011
1	Biological ProductsIBA 01/2011
1	OvalbuminIBA 01/2011
1	oxidized low density lipoproteinIBA 11/2010
1	LDL Lipoproteins (beta Lipoproteins)IBA 11/2010
1	heparanaseIBA 01/2009
1	NF-kappa B (NF-kB)IBA 01/2009
1	HydrolasesIBA 01/2009
1	Peptide Hydrolases (Proteases)FDA Link 01/2009
1	Glucose (Dextrose)FDA LinkGeneric 06/2005
1	Fatty Acids (Saturated Fatty Acids)IBA 06/2005
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2004
1	tert-ButylhydroperoxideIBA 02/2004
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 10/2003

Therapy/Procedure

5	Therapeutics 05/2015 - 10/2010
5	Drug Therapy (Chemotherapy) 05/2015 - 01/2012
1	Bariatric Surgery 01/2018